Weba. : a failure to function. preventing a breakdown of the health-care system. b. : failure to progress or have effect : disintegration. a breakdown of negotiations. c. medicine : a … M followed by a 0 or 1 indicates whether the cancer has spread to distant organs -- for example, the lungs, liver, or bones. M0:No distant spread is found on x-rays (or other imaging tests) or by physical exam. cM0(i+):Small numbers of cancer cells are found in blood or bone marrow (found only by special tests), or … See more T followed by a number from 0 to 4 describes the main (primary) tumor's size and if it has spread to the skin or to the chest wall under the breast. Higher T numbers mean a larger tumor and/or wider spread to tissues … See more N followed by a number from 0 to 3 indicates whether the cancer has spread to lymph nodes near the breast and, if so, how many lymph nodes are involved. Lymph node staging for breast cancer is based on how the … See more

Breakdown Definition & Meaning - Merriam-Webster

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