WebNov 27, 2024 · Cisplatin piglets had lower cardiac index, higher vascular resistance, lower renal blood flow and lower urine output than control piglets. Plasma levels of ADH and urine levels of aquaporin-2... WebAug 20, 2024 · Platinum concentrations in the dialysate showed that platinum can be excreted by peritoneal dialysis. In total, approximately an amount of 0.4–0.5 mg cisplatin and 3–5 mg carboplatin was excreted after the first NIPD course after administration of cisplatin and carboplatin.
Abstract Evaluating Allarity’s DRP® Companion Diagnostic for …
WebJan 3, 2024 · All of these drugs can affect the glomerulus, tubules, interstitium, or renal microvasculature via different mechanisms, with clinical manifestations that range from … WebMar 23, 2024 · Here, we postulated that systemically delivered rapamycin perfluorocarbon nanoparticles (PFC NP) could reach the injured kidneys at sufficient and sustained concentrations to mitigate cisplatin-induced acute kidney injury and preserve renal function. Using fluorescence microscopic imaging and fluorine magnetic resonance … including reflection in e-learning
Exploring the Metabolic Differences between Cisplatin- and UV …
WebApr 14, 2024 · In order to find the most significant changes between ABs induced by cisplatin and ABs induced by UV light, partial least squares-discriminant analyses (PLS-DA) were performed for both sequences. Unlike PCA, PLS-DA is a supervised multivariate analysis that relies on the class membership of each observation. WebCisplatin is the first choice treatment in mediastinal germ cell tumors. However, concerns regarding increased toxicity of cisplatin hamper its administration in patients with … WebJun 1, 2024 · Cisplatin, the most studied drug, was associated with adverse events in all three patients to whom it was administered, ranging from severe (e.g. grade 3−4 ototoxicity, grade 3 anemia, hypotension, neutropenia) to more tolerated ones (e.g. tinnitus, grade 2 peripheral neuropathy) (Eads et al., 2016; Lee and Fabbro, 2005; Sebestyen et al., 2010 ). including references in cv