WebAbstract: High-mobility group AT-hook 2 (HMGA2) is involved in a wide spectrum of biological processes and is upregulated in several tumors, but its role in renal carcinoma remains unclear. WebFeb 22, 2024 · The high mobility group AT-hook 2 gene is an embryonic nuclear factor that mediates epithelial to mesenchymal transition in various tumor models, and it was among the genes overexpressed in endometrial carcinosarcomas. High mobility group AT-hook 2 overexpression was confirmed in 54% of endometrial carcinosarcomas by quantitative …
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http://www.cnreagent.com/show1001180/product_93189.html WebJan 23, 2007 · High mobility group protein HMG-I/HMG-Y Short names HMG-I (Y) Alternative names High mobility group AT-hook protein 1 ( High mobility group protein A1) High mobility group protein R Gene names Name HMGA1 Synonyms HMGIY Organism names Organism Homo sapiens (Human) Taxonomic identifier 9606 NCBI Taxonomic lineage flintstones tycoon
Entry - *600701 - HIGH MOBILITY GROUP AT-HOOK 1; HMGA1
WebGenes Involved and Proteins Gene name HMGA2 (high mobility group AT-hook 2) Location 12q14.3 Protein description probable role in regulation of cell proliferation (transcriptional regulation of cell cycle and DNA repair genes Result of the Chromosomal Anomaly Description ectopic expression of HMGA2 Highly cited references WebMar 25, 2015 · Specifically, HMGA1a contains additional 11 amino acids between the first two AT-hook domains if compared with HMGA1b, and both are lacking the COOH-domain that, conversely, is present in HMGA2 ( 7 ). In addition, HMGA1a and HMGA1b are different from HMGA2 in at least two amino acidic stretches of 25 and 12 residues, respectively. WebJul 28, 2024 · Save this study Bintrafusp Alfa in High Mobility Group AT-Hook 2 (HMGA2) Expressing Triple Negative Breast Cancer The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. greater than 50%