Tīmeklis2024. gada 18. marts · LAMP2B is the predominant isoform expressed in cardiomyocytes. This study evaluates the efficacy of human LAMP2B gene transfer … Tīmeklis2024. gada 25. marts · When comparing LAMP2A with LAMP2B endosomes, the distribution of the different components was asymmetric. Higher levels of TSG101 …

重组人LAMP2B蛋白 Abcam中文官网

TīmeklisAn increase in LAMP2B transcript was seen only in mice treated with 2 × 10 14 vg/kg AAV9.LAMP2B versus PBS controls at the 12-week time point, which was consistent with the biodistribution/VCN data, indicating that higher vector doses are necessary to enable efficient expression of LAMP2B in skeletal muscle compared with the liver … TīmeklisThe fusion protein HuR-Lamp2b and Lamp2b-HuR were detected in the exosomes derived from HuRLamp2b and Lamp2b-HuR-transfected cells ( Supplementary Figure 1), suggesting that both Lamp2b fusion ... how to add delete button in javascript

Entry - *309060 - LYSOSOME-ASSOCIATED MEMBRANE PROTEIN …

TīmeklisLAMP2 has 3 distinct isoforms, LAMP2A, 2B & 2C which are expressed in different tissues and differ in sequence at the extreme C-terminus. Database link: P13473 … Tīmeklis2024. gada 6. sept. · As a proof-of-principle study, RNA-binding protein HuR was fused to the C-terminus of Lamp2b, a membrane protein localized in both exosome and lysosome. The fusion protein was able to be incorporated into the exosomes. Moreover, exosomes engineered with Lamp2b-HuR successfully decreased the abundance of … Tīmeklis2011. gada 20. marts · Delivery of therapeutic siRNA to specific tissues is a major challenge. Alvarez-Erviti et al. show that exosomes—small vesicles that are naturally secreted by many animal cells—can be ... me thinks something is rotten in denmark