Mitf protein atlas

Author: gqmb

August undefined, 2024

WebThe CATGTG motif is consistent with the consensus sequence recognized by a large family of transcription factors with a basic helix-loop-helix structure, which prompted us to examine the possible involvement of a ubiquitous transcription factor, USF, and a novel factor, microphthalmia-associated transcription factor (MITF), recently cloned as the human … http://genome.cse.ucsc.edu/cgi-bin/hgGene?hgsid=1604921059_rVn1WbQrVVz6m7V7RtaRB8ojEueA&hgg_section_method_close=1

MITF reprograms the extracellular matrix and focal adhesion in

Web28 sep. 2024 · The authors also conducted an in silico analysis using TCGA Pan-Cancer-Atlas data to confirm that patients with MITF-E318K melanoma carriers harboured a common pattern of 9p21.3 deletion. The overall results provided greater insights into the clinical strategies that could be used to manage and treat MITF-associated tumour types. WebThe activity and degradation of MITF-M are regulated by extracellular signals via protein phosphorylation, such as c-Kit signaling. Together, multiple signals appear to converge on the M promoter as well as on MITF proteins, leading to the proper regulation of MITF-M in melanocytes and other MITF isoforms in many cell types. how much sea buckthorn should you take

MITF transcriptomics data - The Human Protein Atlas

WebCell atlas. Showing subcellular location of MITF (bHLHe32, MI, WS2, WS2A). We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again. WebCell type atlas. Showing single cell type specific RNA data of MITF (bHLHe32, MI, WS2, WS2A). how do side curtain airbags work

Human Gene MITF (ENST00000394351.9) from GENCODE V43

Brain tissue expression of MITF - Summary - The Human Protein Atlas

WebAtlas. Tissue i. The Tissue section contains information regarding the expression profile of human gene both on the mRNA and protein level. The protein expression data from 44 … Web15 jul. 2002 · The MITF cDNA was excised with EcoRI and subcloned into vector pCMV5a (Sigma Chemical Co., St Louis, MO). The orientation and sequence of the MITF cDNA was verified by automated DNA sequencing. Expression of functional MITF protein was verified by co‐transfection of pCMV5a‐MITF with a TYRP1 promoter plasmid in HeLa cells. Gel … how much sculptra is neededWeb26 dec. 2024 · Brassinin is a phytoalexin abundant in plants, especially in cabbage, and has been reported to act as an anti-cancer and anti-inflammatory agent. However, limited studies are available to elucidate the functionalities of brassinin. Here, we tested the effects of brassinin on melanogenesis using cell-free and cell-based biochemical analysis and … how do side bets work in blackjack

"WebProduct Description Polyclonal Antibody against Human MITF Alternative Gene Names bHLHe32, MI, WS2, WS2A Open Datasheet Price $505.00 Product Number HPA003259 Unit Size Concentration 0.1 mg/ml Availability >10 in Stock Ships Ready to Ship Share by E-mail Add to Cart Show all images [5 pictures] " - Mitf protein atlas

Mitf protein atlas

Expression of MITF in cancer - Summary - The Human Protein Atlas

Web15 nov. 2024 · The Cancer Genome Atlas (TCGA) melanoma dataset revealed three transcriptionally distinct subtypes that are enriched for immune genes, for keratinocyte genes, or have low expression of the melanocyte-inducing transcription factor (MITF) and its targets as well as high expression of neuronal genes (called the MITF-low signature; ref. 2). Web5 dec. 2024 · Indeed, MITF functions as a central regulator of melanocyte differentiation and melanogenesis by controlling the transcription of a panel of genes, including melan-A (MART1), tyrosinase and premelanosome protein PMEL17 (PMEL/SILV/gp100) [36,37,38], which encode proteins that have been reported to be tumor-specific antigens [39, 40].

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WebRabbit polyclonal MITF antibody. 100% Bioguaranteed. US EN. Applications Products Services Support. All Photos (3) SAB4501879. Anti-MITF antibody ... Prestige Antibodies ® Powered by Atlas Antibodies, affinity isolated antibody, buffered ... Anti-MITF Antibody detects endogenous levels of total MITF protein. MITF (microphthalmia-associated ... Webmedicinal, diagnostic or therapeutic use. No products from Atlas Antibodies may be resold, modified for resale or used to manufacture commercial products without prior written approval from Atlas Antibodies AB Rev. December 2012 Atlas Antibodies AB Phone +46(0)8 54 59 58 50 IBAN SE91 6000 0000 0004 6991 6761 Bankgiro 5469-1092

WebWaardenburg Syndrome Type 2A. Tassabehji et al. (1994) demonstrated mutations in the MITF gene in affected individuals in 2 families segregating Waardenburg syndrome type 2A (WS2A; 193510).Both mutations affected splice sites in the MITF gene. One might expect that the MITF mutations would result in abnormal proteins which, when combined with … WebExpression of MITF in cancer - Summary - The Human Protein Atlas MITF PATHOLOGY ATLAS GENE/PROTEIN Antibody validation Dictionary Level of antibody staining/expression High Medium Low Not detected PROGNOSTIC SUMMARY Prognostic marker in renal cancer (favourable).

Web1 jan. 2024 · To clarify the molecular mechanism underlying Nrf3-mediated melanogenesis in response to Fsk, we investigated the effect of Nrf3 overexpression on Mitf gene expression, which encodes a master regulator of melanogenesis. 17 Mitf mRNA and protein levels were elevated in Fsk-treated oeNrf3 cells in comparison to Fsk-treated … WebCell atlas. Showing subcellular location of MITF. We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies.

Web16 jan. 2024 · In melanocytes, cAMP activates protein kinase A (PKA), which phosphorylates and activates the cAMP response element-binding protein (CREB). CREB is a component of a transcription factor complex that drives transcription of microphthalmia-associated transcription factor (MITF), which is known as the master regulator of …

Webhuman brain protein location i The Human brain protein data is based on curated and manually selected Tissue Atlas data. The standard brain regions used in the Tissue … how do sidewinder snakes moveWebprotein_coding_gene Location ... Waardenburg's syndrome; and familial melanoma. Orthologous to human MITF (melanocyte inducing transcription factor). Genome Resources. Alliance ; Gene:30080 ; VEGA:OTTDARG00000019915 ; Ensembl(GRCz11):ENSDARG00000003732 ; Note None Comparative ... Expression … how much sea level rise per yearWeb28 feb. 2024 · Protein existence level: PE1 Quaternary structure: Homodimer and heterodimer; with TFE3 or MITF (PubMed:15507434, 1748288). Interacts (when phosphorylated by MTOR) with YWHAZ; promoting retention in the cytosol (PubMed:35662396). Sequence caution: The sequence AAA36730.1 differs from that … how much sea buckthorn oil is needed daily